Nanoparticulate Drug Delivery System

Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. This expertly written guide addresses the scientific methodologies, formulation, processing,applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS, including lipid nanoparticles for dermal applications, nanocarriers for the treatment of restenosis, ocular, central nervous system, and gastrointestinal applications, and use as an adjuvant for vaccine development.




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Polymers in Drug Delivery

In recent years there has been an explosion in the use of polymers to solve various biomedical problems. Polymers play a crucial role in controlling drug release rate, enhancing drug solubility and uptake, and limiting drug degradation and toxicity. Polymers in Drug Delivery is a state-of-the-art documentation and review of all areas in which polymers are used in drug delivery, including hydrogels, soluble polymer drug conjugates, polymeric vesicles and micelles, microspheres, nanoparticles, polymeric in tissue engineering, and more. It is a readily accessible volume suitable for drug delivery scientists and as reading for advanced pharmaceutics students and others new to the field.


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http://rapidshare.com/files/160142693/tpoly_dd.zip

Practical Guide to Clinical Data Management

Clinical data management (CDM) has changed from being an essentially clerical task in the late 1970s and early 1980s to a highly computerized, highly specialized field today. Clinical data managers have had to adapt their data management systems and processes accordingly. Practical Guide to Clinical Data Management steers readers through the role of data management in clinical trials and includes more advanced topics such as CDM systems, SOPs, and quality assurance. It helps readers establish GCP, manage laboratory data, ensure that DMB systems are in compliance with federal regulations, and deal with the kinds of clinical data that can cause difficulties in database applications.
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http://rapidshare.com/files/126960497/Pra_gud_clin_dm2Ed.zip

pharmacokinetics in Drud Discovery and Development

Pharmacokinetics has evolved from its origin into a complex discipline with numerous subspecialties and applications in patient management, drug development, and regulatory issues. This expansion has made it difficult for any one individual to become a full-fledged expert in all areas. Fulfilling the need for a wide-ranging guide to the many existing subspecialties in this field, Pharmacokinetics in Drug Discovery and Development details the different areas in the field providing the ideal comprehensive, quick access text and reference. After an introduction of basic principles, the book is divided into sections that coverindustrial and regulatory applications, clinical applications, and research applications. The following sections cover such topics as PK/PD approaches, clinical pharmacokinetic monitoring, population pharmacokinetics, linear systems approaches, and more. Fourteen authors, each an expert in his/her area of expertise, provide an extensive background into the subspeciality with emphasis on the section's theme. Covering the many sub-disciplines and providing pharmacokinetic concepts, terminology, and approaches, Pharmacokinetics in Drug Discovery and Development serves as a resource for professionals throughout this field.

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http://rapidshare.com/files/154775989/tpharmacok_ddd.zip

Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form

this book covers every stage of drug development, from candidate drug selection to commercial formulation. It provides practical reference and pragmatic guide on what studies need to be undertaken, for what reasons, and at what key stages of the drug development process. Going beyond coverage of preformulation, the book discusses biopharmaceuticals, drug delivery, formulation, and process development aspects of product development. The contributing authors share their experience and expertise in significant chaptersdivided into three useful sections: Aiding Candidate Drug Selection, Early Drug Development, and From Product Design to Commercial Dosage Form. 


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Developing Solid oral Dosage Forms Pharmaceutical Theory and practice

This book is completely focussing on how to develop a Solid Dosage Form with their properties:

Scientists entering the pharmaceutical industry today often lack the fundamental knowledge that is reflected in the chapters contained in this book. Many of the researchers entering industry have backgrounds in chemical engineering or organic chemistry. Their exposure to the principles of physical pharmacy is a deficit that must be overcome by on-the-job training and by extensive study. It is in the areas of preformulation,the development of new and sophisticated drug delivery systems, and the day-to-day work of optimizing the effects of new drug entities that this knowledge is most needed. There are, of course, many textbooks that deal with specific subjects important to the industrial pharmacist, focusing on tablets, capsules, disperse systems, parenterals, etc. However, there is a critical need for a comprehensive treatment of the science underlying each of these special areas, together with practical applications of the science that results in quality dosage forms. Questions related to solubility, dissolution, chemical and physical stability, interfacial phenomena, and the absorption and distribution of drug molecules are common to all. Consequently, a single textbook that brings together experts in all of these subjects can be an invaluable asset to the novice industrial scientist. Each chapter in this book contains a useful bibliography of references that can provide for ready access to current research in the field. We should be grateful that these authors have taken time from their busy schedules to share their knowledge and experience with all of us.

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Pharmaceutical_Theory___Practice.pdf

Handbook of Pharmceutical Manufacturing Formulations

This book is completely focussing on the manufacturing of formulations mainly selecting the Semi-Solid Products:

The semisolid drugs category is comprised of ointments,

creams, gels, suppositories, and special topical dosage

forms. The formulations of semisolid drugs share many

common attributes of consistency, presentation, preservation

requirement, and the route of administration, mainly

topical. As a result, grouping them together for the purpose

of defining common formulation practices and problems

is justified. The topical dosage forms present unique

opportunities to design novel drug delivery systems such

as patches and other transdermal systems. Some of these

are described in the volume, but the reader is referred to

specific patents issued, wherein greater details are readily

obtainable.

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http://rapidshare.com/files/421897697/Handbook_of_Pharmaceutical_Manufacturing_Formulations_Semisolids_Products.pdf